{"id":39,"date":"2020-01-31T21:22:53","date_gmt":"2020-01-31T21:22:53","guid":{"rendered":"https:\/\/ami.advancedrenaleducation.com\/wparep\/emea\/?page_id=39"},"modified":"2020-02-19T21:57:32","modified_gmt":"2020-02-19T21:57:32","slug":"glossary","status":"publish","type":"page","link":"https:\/\/ami.advancedrenaleducation.com\/wparep\/emea\/glossary\/","title":{"rendered":"Glossary"},"content":{"rendered":"[vc_section el_class=”shadow-box-sec” css=”.vc_custom_1582149029365{background-color: #ffffff !important;}”][vc_row css=”.vc_custom_1582149111962{padding-top: 10px !important;padding-right: 20px !important;padding-bottom: 10px !important;padding-left: 20px !important;}” el_class=”glossary-row”][vc_column][vc_column_text]<\/a>
All<\/a> | A<\/a> B<\/a> C<\/a> D<\/a> E<\/a> F<\/a> G<\/a> H<\/a> I<\/a> K<\/a> L<\/a> M<\/a> N<\/a> O<\/a> P<\/a> R<\/a> S<\/a> T<\/a> U<\/a> V<\/a> <\/div>
There are currently 308 terms in this directory<\/div>
<\/a>AAMI<\/strong>
Association for the Advancement of Medical Instrumentation that develops voluntary standards for aspects of dialysis, including water treatment and dialyzer reprocessing.<\/div><\/div>
<\/a>Acid Clean<\/strong>
Pertaining to a hemodialysis system: A daily process where acid (vinegar) is rinsed through the acid and bicarbonate lines.<\/div><\/div>
<\/a>Acidosis<\/strong>
A pathologic condition resulting from accumulation of acid or depletion of the alkaline reserve (bicarbonate) content of the blood and body tissues, and characterized by an increase in hydrogen ion concentration (decrease in pH).<\/div><\/div>
<\/a>Acute <\/strong>
Rapidly developing; severe; short duration.<\/div><\/div>
<\/a>Acute Renal Failure<\/strong>
A sudden loss of kidney function; it can be reversible.<\/div><\/div>
<\/a>Air Embolism<\/strong>
Occurs when air bubbles enter the bloodstream and are carried into a vessel small enough to be blocked by the air, where it acts like a clot, blocking the flow of blood.<\/div><\/div>
<\/a>Alkalosis<\/strong>
A pathological condition resulting from accumulation of bicarbonate and is characterized by a decrease in hydrogen ion concentration and increase in pH.<\/div><\/div>
<\/a>Allergic Reaction<\/strong>
Local or general hypersensitivity reaction following contact with a specific allergen.<\/div><\/div>
<\/a>Ambulatory<\/strong>
Moving or walking around.<\/div><\/div>
<\/a>Anaphylaxis<\/strong>
Anaphylaxis or anaphylactic reaction is an immediate, severe reaction to a substance to which an individual is allergic. The reaction may include signs and\/or symptoms such as hives, itching or wheezing. The reaction may develop into anaphylactic shock, which can cause life-threatening consequences such as hypotension, cardiac arrhythmias or arrest, spasms of the breathing passages and swelling of the throat.<\/div><\/div>
<\/a>Anemia<\/strong>
A deficiency of the oxygen carrying pigment of hemglobin often accompanied by a reduced number of circulating red blood cells; common in patients on dialysis due to decreased red blood cell production and procedural blood loss. The major symptoms are fatigue, tiredness, breathlessness on exertion, pallor and poor resistance to infection<\/div><\/div>
<\/a>Anticoagulant<\/strong>
Substance that delays or prevents coagulation of blood.<\/div><\/div>
<\/a>Antiseptic<\/strong>
A chemical which prevents or inhibits growth and reproduction of bacteria; it does not necessarily destroy them as a disinfectant would<\/div><\/div>
<\/a>Anuric<\/strong>
Absence of urine formation.<\/div><\/div>
<\/a>Arrhythmia<\/strong>
Irregular heart beat, rapid or slow pulse, palpitations caused by changes in the blood pH or electrolyte levels (potassium), hypotension or heart disease<\/div><\/div>
<\/a>Arterial Drip Chamber<\/strong>
Chamber within the hemodialysis system extracorporeal circuit were arterial pressure is monitored. A bubble trap inside the drip chamber collects any air that enters the blood tubing.<\/div><\/div>
<\/a>Arterial line<\/strong>
Part of the hemodialysis system extracorporeal circuit that is involved with transporting the patient\u2019s blood to the dialyzer.<\/div><\/div>
<\/a>Arterial Side of Dialyzer<\/strong>
The end of the dialyzer where the patient\u2019s blood enters to be dialyzed.<\/div><\/div>
<\/a>As-treated analysis<\/strong>
An analysis in which only the test subjects who actually received the intervention or medication to be examined during the study are considered in the results analysis. <\/div><\/div>
<\/a>Aseptic<\/strong>
Free from infectious organisms; sterile.<\/div><\/div>
<\/a>Aseptic Technique<\/strong>
A process of rendering an object completely free of microorganisms. A method usually involving sterile gloves, gowns and masks.<\/div><\/div>
<\/a>Assisted Home Dialysis<\/strong>
For patients unable to perform treatment themselves, assistance can be provided by care partners or visiting caregivers such as nurses to overcome the barriers to performing dialysis at home. Non-assisted home dialysis refers to patients performing their home treatment independently, without the help or presence of a partner or need for additional external support.<\/div><\/div>
<\/a>Assisted PD<\/strong>
The administration of peritoneal dialysis (PD) modalities to a physically dependent patient by a home-visiting nurse, a caregiver or a family member.<\/div><\/div>
<\/a>Auto Flow Rate<\/strong>
A ratio of dialysate flow to blood flow based on the dialysis prescription, for example 2x dialysate auto flow with a blood flow of 400ml\/min would be 800 ml\/min.<\/div><\/div>
<\/a>Automated PD (APD)<\/strong>
A number of different PD modalities that use an automated peritoneal dialysis (PD) machine.<\/div><\/div>
<\/a>Automated PD machine<\/strong>
An electrical appliance specifically designed to perform peritoneal dialysis (PD) automatically, also known as a \"cycler\".<\/div><\/div>
<\/a>Back Pain<\/strong>
Pain or discomfort located in the posterior regions of the trunk, including the thoracic, lumbar, sacral, or adjacent regions.<\/div><\/div>
<\/a>Bacteria<\/strong>
Single cell organisms, fully capable of rapid reproduction. They are prevalent everywhere; some are harmless, others known to produce infectious diseases.<\/div><\/div>
<\/a>Bicarbonate<\/strong>
A buffer used by the body to neutralize acids that form when the body breaks down protein and other foods.<\/div><\/div>
<\/a>Biocompatibility<\/strong>
The quality of not having toxic or injurious effects on biological systems.<\/div><\/div>
<\/a>Biocompatible PD solutions<\/strong>
Peritoneal dialysis (PD) solutions with characteristics like low GDP concentration, near neutral pH, low concentration of lactate buffer (some biocompatible solutions use bicarbonate as a buffer and others use a mixture of bicarbonate and low lactate concentrate).<\/div><\/div>
<\/a>Blood Circuit<\/strong>
Component of the hemodialysis system that is enclosed within the arterial blood line, dialyzer fibers and the venous blood line. It is also referredto as the extracorporeal circuit.<\/div><\/div>
<\/a>Blood Flow Rate<\/strong>
See blood pump speed.<\/div><\/div>
<\/a>Blood Line Set<\/strong>
Part of the extracorporeal circuit that carries blood from the patient\u2019s vascular access through the arterial needle or catheter port, to the dialyzer, and back to the patient through the venous needles or catheter port. There are two segments of blood tubing: arterial (red connector colored) and the venous (blue connector colored). Other components of the blood tubing include patient connectors, dialyzer connectors, arterial and venous drip chambers, blood pump segment, heparin and saline infusion lines.<\/div><\/div>
<\/a>Blood Pressure<\/strong>
The pressure exerted against vessel walls resulting from the pumping force of the heart and resistance of blood vessels. It is measured by auscultating (listening to) the changing sounds produced by varying external pressures on an artery.<\/div><\/div>
<\/a>Blood Protein<\/strong>
A complex substance or very large nitrogen containing molecule found in blood.<\/div><\/div>
<\/a>Blood Pump<\/strong>
Part of the hemodialysis delivery system that moves the patient\u2019s blood through the extracorporeal circuit at a fixed rate of speed when the blood pump segment is threaded between the pump head and the rollers.<\/div><\/div>
<\/a>Blood Pump Door<\/strong>
Cover of the blood pump.<\/div><\/div>
<\/a>Blood Pump Housing<\/strong>
Component of the hemodialysis machine that holds the blood pump rotor and tubing guides.<\/div><\/div>
<\/a>Blood Pump Speed<\/strong>
Prescribed rate of blood programmed on the blood pump.<\/div><\/div>
<\/a>Body Mass Index (BMI)<\/strong>
Anthropometric index defined as weight in kilograms\/(stature in m2)2.<\/div><\/div>
<\/a>Bolus<\/strong>
A relatively large, single dose.<\/div><\/div>
<\/a>BUN (Blood Urea Nitrogen)<\/strong>
Nitrogen in the blood in the form of urea. It is a result of protein breakdown due to dietary intake (digestion) or inherent bodily tissue breakdown. An increase usually indicates decreased kidney function.<\/div><\/div>
<\/a>Bypass Mode<\/strong>
Bypass mode occurs when the dialysate conductivity or temperature goes outside alarm limits. In bypass mode, valves inside the hemodialysis machine redirect the flow of dialysate to bypass the dialyzer internally until temperature and conductivity are back within acceptable limits.<\/div><\/div>
<\/a>Cardiac Tamponade<\/strong>
A pathological condition which results from excess accumulation of fluid in the pericardium.<\/div><\/div>
<\/a>Catheter<\/strong>
Catheter A tubular, flexible instrument, passed through body channels for withdrawal of fluids from (or introduction of fluids into) a body cavity.<\/div><\/div>
<\/a>Catheter extension<\/strong>
A piece of tubing connecting the catheter to the peritoneal dialysis (PD) delivery system.<\/div><\/div>
<\/a>Catheter-related peritonitis (or exit site- or tunnel infection-related peritonitis)<\/strong>
A peritonitis episode in conjunction with an exit-site or tunnel infection with the same organism as that at the exit site.<\/div><\/div>
<\/a>Center for Medicare and Medical Services (CMS)<\/strong>
The U.S. federal agency that runs the Medicare, Medicaid, and Children\u2019s Health Insurance Programs, and the federally facilitated Marketplace.<\/div><\/div>
<\/a>Charlson Comorbidity Score\/Index<\/strong>
A validated, simple method of categorizing comorbidities in patients that predicts 10-year survival.<\/div><\/div>
<\/a>Chemical Rinse<\/strong>
The \u201cChemical\/Rinse program of the hemodialysis machine disinfects the machine by rinsing it with water, chemical disinfectant, and water again.<\/div><\/div>
<\/a>Chemoreceptor<\/strong>
A sense organ or sensory nerve ending that is stimulated by and reacts to certain chemical stimuli. It is located outside of the central nervous system.<\/div><\/div>
<\/a>Chest Pain<\/strong>
Pressure, burning, or numbness in the chest.<\/div><\/div>
<\/a>Chronic<\/strong>
Of long duration or recurring frequently.<\/div><\/div>
<\/a>Chronic Kidney Disease<\/strong>
Persistent, long-lasting renal pathologic process, often associated with loss of kidney function.<\/div><\/div>
<\/a>Chronic kidney disease - mineral and bone disorder (CKD-MBD)<\/strong>
A disorder that can affect the bones, heart, and blood vessels of a person with CKD that is caused by changes in calcium, phosphate, and hormonal levels that occur with kidney disease.<\/div><\/div>
<\/a>Chronic Renal Failure<\/strong>
The progressive, irreversible loss of kidney function that occurs over periods of time ranging from a few months to decades. Also called Chronic Renal Insufficiency.<\/div><\/div>
<\/a>Clean Technique<\/strong>
Rendering an object partially free from organisms.<\/div><\/div>
<\/a>Clearance<\/strong>
A quantitative measure, expressed in mL\/minute, of the rate at which waste products are removed from the blood by the kidney, peritoneal membrane or artificial kidney.<\/div><\/div>
<\/a>Clot<\/strong>
A mass of coagulated blood. The normal reaction of the blood to a damaged blood vessel or foreign material.<\/div><\/div>
<\/a>Coagulation<\/strong>
The process of forming a blood clot.<\/div><\/div>
<\/a>Coefficient<\/strong>
A numerical measure of a physical or chemical property that is constant for a system under specified conditions.<\/div><\/div>
<\/a>Comprehensive Conservative Management (CCM)<\/strong>
Holistic patient-centered care for CKD-5 patients who require KRT but opt out of dialysis treatment or kidney transplant. CCM includes interventions to delay the progression of kidney disease, shared decision-making, active symptom management, detailed communications including advanced care planning, palliative care, psychological support, social and family support, and cultural and spiritual domains of care.<\/div><\/div>
<\/a>Concentrate<\/strong>
Pertaining to hemodialysis: One of two salt solutions (acid and bicarbonate) that are mixed together with purified water to form dialysate.<\/div><\/div>
<\/a>Conductivity<\/strong>
The ability of a fluid to transfer electrical charge as a measurement of ions in a solution.<\/div><\/div>
<\/a>Conductivity Meter<\/strong>
Measures the electrolyte composition of dialysate to ensure it is within safe limits for use.<\/div><\/div>
<\/a>Confidence interval ( 95 % CI )<\/strong>
A range of estimate values that you can be 95 percent confident contains the true value of the parameter being measured.<\/div><\/div>
<\/a>Connecting device<\/strong>
A device of different designs (exclusively specific for each peritoneal dialysis (PD) delivery system) used for the connection of the catheter or its extension to the delivery sytem. Synonym to connector.<\/div><\/div>
<\/a>Contaminate<\/strong>
To make unclean, unsterile or impure.<\/div><\/div>
<\/a>Continuous ambulatory peritoneal dialysis (CAPD)<\/strong>
A peritoneal dialysis (PD) modality where a certain amount of dialysate is always present in the peritoneal cavity resulting in a continuous dialysis method. Four daily exchanges are typically performed manually using gravity or in some cases with the use of an assisting device.<\/div><\/div>
<\/a>Continuous cycling peritoneal dialysis (CCPD)<\/strong>
An automated PD (APD) modality with a number of exchanges during the night and a long daytime dwell. All exchanges are performed by a cycler.<\/div><\/div>
<\/a>Continuous cycling peritoneal dialysis plus or enhanced(CCPD plus or enhanced CCPD)<\/strong>
Continuous cycling peritoneal dialysis (CCPD) with the addition of at least one daytime manual exchange.<\/div><\/div>
<\/a>Continuous flow peritoneal dialysis(CFPD)<\/strong>
A peritoneal dialysis (PD) modality where dialysate flows continuously in and out of the peritoneal cavity through two separate catheters or one dual lumen catheter.<\/div><\/div>
<\/a>Contraindication<\/strong>
Symptom, condition or circumstance that renders the use or a remedy or procedure inadvisable, usually because of a risk.<\/div><\/div>
<\/a>Convulsion<\/strong>
Violent involuntary contraction or series of contractions of voluntary muscles. Also known as seizure.<\/div><\/div>
<\/a>Corrosive<\/strong>
Slow disintegration or wearing away of something by a destructive agent.<\/div><\/div>
<\/a>Cost-effectiveness analysis<\/strong>
An evaluation of the effectiveness of \u22652 treatments in relation to their cost. The aim of the decision maker when assessing a new intervention is to maximize outcomes (i.e., quality-adjusted life years) and minimize opportunity costs. Cost effectiveness analysis is the method used to measure these outcomes.<\/div><\/div>
<\/a>Cramping<\/strong>
During the hemodialysis treatment: Painful muscle cramps often in the hands and feet resulting from removal of too much fluid, changes in blood chemistry, especially sodium, low potassium levels and hypotension.<\/div><\/div>
<\/a>Creatinine<\/strong>
Creatinine is a waste product of creatinine phosphate metabolism, which is found especially in the muscle and blood. Increased creatinine values inthe blood can be an indication of renal failure. It is one of the primary lab values indicating a patient's need to start dialysis.<\/div><\/div>
<\/a>Crenation<\/strong>
Conversion of normally round red blood cells into shriveled, irregularly shaped forms that occurs if the blood is exposed to a solution that is more concentrated than blood.<\/div><\/div>
<\/a>Culture negative peritonitis<\/strong>
The appearance of cloudy effluent (with more than 50% polymorphonuclear white blood cells) and abdominal pain with persistently (>3) negative cultures of peritoneal effluent.<\/div><\/div>
<\/a>Cumulative incidence of death<\/strong>
The proportion of a group that dies over a defined time interval.<\/div><\/div>
<\/a>Cycle<\/strong>
A peritoneal cycle or exchange is the infusion and drainage of a specific volume of peritoneal dialysis solution consistent with the PD prescription. The PD prescription defines the volume, dwell time and sometimes the rate of infusion and drainage. The dwell time may vary from a few minutes to several hours.<\/div><\/div>
<\/a>Cycler<\/strong>
A machine used to infuse and drain dialysate from the peritoneal cavity.<\/div><\/div>
<\/a>Dehydration<\/strong>
Excessive water loss from the body, organ or bodily part. This occurs when output of water exceeds intake.<\/div><\/div>
<\/a>Dextrose (Glucose)<\/strong>
A form of sugar used in dialysate to remove fluid.<\/div><\/div>
<\/a>Dialysate (dialysis fluid) <\/strong>
A mixture of water, electrolytes and dextrose. Sodium lactate is the most commonly used buffer in the dialysis solution. Newer solutions using pure bicarbonate or bicarbonate\/lactate combinations have been developed as a more physiological buffer. Electrolyte levels in dialysate are proportioned to ensure that the levels in the blood remain within physiological range. Waste products, such as BUN and creatinine are not present in the dialysate and will readily move out of the blood into the dialysis fluid.<\/div><\/div>
<\/a>Dialysate Circuit<\/strong>
Component of the dialysis system that is enclosed within the hydraulic system and the dialysate compartment (outside the fibers) of the dialyzer.<\/div><\/div>
<\/a>Dialysate container<\/strong>
In peritoneal dialysis: The bag containing the dialysate, also known as the \u201cperitoneal dialysis bag\u201d.<\/div><\/div>
<\/a>Dialysate Flow Rate<\/strong>
A prescribed ml\/min flow of the dialysate through the dialyzer.<\/div><\/div>
<\/a>Dialysate fresh<\/strong>
The unused dialysate<\/div><\/div>
<\/a>Dialysate leak (peritoneal)<\/strong>
Extravasation of the fluid to any space outside the peritoneal cavity (e.g. pleural cavity, through the exit site or the surgical incision, scrotum).<\/div><\/div>
<\/a>Dialysate spent<\/strong>
The dialysate drained out after its dwell in the peritoneal cavity, also known as effluent.<\/div><\/div>
<\/a>Dialysis<\/strong>
Diffusion of blood across a semi-permeable membrane to remove toxic substances. Dialysis maintains fluid, electrolyte and acid-base balance when there is impaired kidney function or there are no native kidneys.<\/div><\/div>
<\/a>Dialyzer Reaction<\/strong>
Can be caused by a reaction to ethylene oxide with symptoms occurring in the first 15 \u2013 30 minutes of treatment that include itching, chest and or back pain, shortness of breath, hypotension, nausea and general discomfort.<\/div><\/div>
<\/a>Diastolic Blood Pressure<\/strong>
The blood pressure against the arteries when the heart is at rest (between beats). It is the bottom half of the blood pressure reading.<\/div><\/div>
<\/a>Diffusion<\/strong>
Process in which solutes move from an area of high solute concentration through a semi-permeable membrane to an area of low solute concentration.<\/div><\/div>
<\/a>Disequilibrium Syndrome<\/strong>
Can occur when the BUN is removed much faster from the blood than from the brain, when disequilibrium occurs, fluid moves into the brain cells and potential symptoms are headache, nausea, hypertension, restlessness, confusion, blurred vision and seizures.<\/div><\/div>
<\/a>Distal<\/strong>
Refers to furthest from the center of the body. For example, the hands and feet are distal extremities. The opposite of proximal.<\/div><\/div>
<\/a>Diurnal PD or daytime PD<\/strong>
A number of manual exchanges during the day with a dry abdomen during the night (for those who need short exchanges and for whatever reason cannot or will not use a cycler).<\/div><\/div>
<\/a>Drain (of PD fluid)<\/strong>
The action of outflow of the spent dialysate from the peritoneal cavity.<\/div><\/div>
<\/a>Drain Time<\/strong>
The amount of time needed for the peritoneal fluid to drain from the peritoneal cavity.<\/div><\/div>
<\/a>Drip Chamber<\/strong>
Used to collect air in the arterial and venous chambers of the hemodialysis system.<\/div><\/div>
<\/a>Dry Weight<\/strong>
The ideal body weight without excess fluid volume.<\/div><\/div>
<\/a>Dwell<\/strong>
The period during which the dialysate remains inside the peritoneal cavity (usually from the end of the infusion to the beginning of drainage).<\/div><\/div>
<\/a>EconLit<\/strong>
An academic literature abstracting database service focused on literature in the field of economics. It is produced by the American Economic Association.<\/div><\/div>
<\/a>Edema<\/strong>
Accumulation of an excessive amount of fluid in or around tissues or cells.<\/div><\/div>
<\/a>Effect of Differing Kidney Disease Treatment Modalities and Organ Donation and Transplantation Practices on Health Expenditure and Patient Outcomes (EDITH) Project<\/strong>
A 36-month project (2017-2020) focusing on the differing CKD treatment modalities, subdivided into six closely interlinked work packages realized by a multinational interdisciplinary team aiming at long-term sustainability of the registers established.<\/div><\/div>
<\/a>Effective peritoneal surface area<\/strong>
The area of the peritoneal surface that is sufficiently close to peritoneal capillaries to play a role in solute and water transport.<\/div><\/div>
<\/a>Efferent<\/strong>
Carrying away from the central organs or section. For example, efferent arterioles carry blood away from the glomeruli of the kidney. The opposite of afferent.<\/div><\/div>
<\/a>Effluent<\/strong>
The used or spent dialysate fluid that is carried to the drain.<\/div><\/div>
<\/a>Electrolytes<\/strong>
An electrolyte is a compound that breaks apart into ions. Common electrolytes include sodium (Na+), potassium (K+) and calcium (Ca++). Electrolyte transport electrical impulses along the nerves to the muscles, including the heart. Healthy kidneys maintain electrolyte balance in the body. Electrolytes are added to dialysate in carefully controlled amounts.<\/div><\/div>
<\/a>Embolus<\/strong>
A mass of undissolved matter present in the blood or lymph brought there by the blood or lymph current.<\/div><\/div>
<\/a>Encapsulating peritoneal sclerosis (former term: Sclerosing encapsulating peritonitis)<\/strong>
A life threatening complication of peritoneal dialysis where an encapsulating sclerotic reaction of the peritoneum develops, with the bowel enveloped in a thick cocoon of fibrous tissue, causing intermittent, partial, or complete bowel obstruction.<\/div><\/div>
<\/a>End Stage Renal Disease<\/strong>
Term used for complete or irreversible loss of kidney function, the last stage of chronic renal failure. Also referred to as ESRD.<\/div><\/div>
<\/a>Endotoxin<\/strong>
A poison harmful to all body tissues, contained within certain Gram negative bacteria and released only when the bacterial cell is broken down or dies and disintegrates.<\/div><\/div>
<\/a>Enteric peritonitis<\/strong>
Infectious peritonitis with an organism consistent with those from the gastrointestinal tract. (Presence of anaerobic organisms is pathognomic of this condition).<\/div><\/div>
<\/a>EPO-equivalent IU\/week<\/strong>
Units of darbepoetin alfa were converted to units of epoetin alfa-equivalent by multiplying by 250.<\/div><\/div>
<\/a>Equilibrium<\/strong>
The body's attempt to maintain balance or homeostasis. Used in reference to equal concentrations in two compartments across a semipermeable membrane.<\/div><\/div>
<\/a>Erythropoietin<\/strong>
A hormone that acts on the bone marrow to stimulate red blood cell production. It is produced by the kidney in response to oxygen deficiency in the tissues.<\/div><\/div>
<\/a>Estimated Dry Weight<\/strong>
The weight the patient would be if the kidneys functioned normally.<\/div><\/div>
<\/a>Etiology<\/strong>
The cause of a disease.<\/div><\/div>
<\/a>European Renal Association - European Dialysis and Transplantation Association (ERA-EDTA)<\/strong>
One of the largest nephrological associations in the world, which supports basic and clinical research in the fields of clinical nephrology, dialysis, kidney transplantation, and related topics.<\/div><\/div>
<\/a>European Society of Organ Transplantation (ESOT)<\/strong>
An international organization dedicated to the pursuit of excellence in organ transplantation, supporting research and extensive education, and promoting changes in European policy.<\/div><\/div>
<\/a>Exchange<\/strong>
A peritoneal exchange or cycle is the infusion and drainage of a specific volume of peritoneal dialysis solution consistent with the PD prescription. The PD prescription defines the volume, dwell time and sometimes the rate of infusion and drainage. The dwell time may vary from a few minutes to several hours.<\/div><\/div>
<\/a>Exit site<\/strong>
The most external part of the sinus tract and the skin surrounding the exit of the catheter tunnel. Usually the location of the exit site is in the abdominal wall, but a presternal exit site is also an option.<\/div><\/div>
<\/a>Exit-site infection<\/strong>
Evidence of inflammation (pain, swelling, erythema, and\/or discharge) at the exit site.<\/div><\/div>
<\/a>Febrile<\/strong>
Body temperature greater than 98.6F or 37.0C.<\/div><\/div>
<\/a>Fibrin<\/strong>
A whitish filamentous protein formed by the action of thrombin on fibrinogen.<\/div><\/div>
<\/a>Fill<\/strong>
Term used in peritoneal dialysis to indicate the action of inflow of the fresh dialysate from its container into the peritoneal cavity.<\/div><\/div>
<\/a>Filtration<\/strong>
Process of a stream of liquid moving through a partition with small holes. Fluid and particles small enough to pass through the partition will, while larger particles will remain.<\/div><\/div>
<\/a>Fluid Overload<\/strong>
State of the patient when dry weight has not been reached, this can lead to congestive heart failure or pulmonary edema.<\/div><\/div>
<\/a>Flush<\/strong>
Peritoneal flush or lavage is the \"rapid\" infusion and drainage of peritoneal dialysis solution with the purpose of removing blood, fibrin, debris or spent dialysate from the peritoneal cavity or catheter. The dwelltime is minimal or non-existent. Or, in terms of the actual exchange procedure itself, to flush is to remove the remaining air from the infusion line into the drainage bag.<\/div><\/div>
<\/a>FREEDOM Study (Following Rehabilitation, Economics and Everyday-Dialysis Outcome Measurements Study)<\/strong>
A multicenter prospective cohort study in which 41 different clinical sites participated.<\/div><\/div>
<\/a>Glomerular Filtration Rate (GFR)<\/strong>
The volume of plasma filtered from the glomerular capillaries into the Bowman's capsule each minute (mL\/min).<\/div><\/div>
<\/a>Glomerulus<\/strong>
A cluster of capillary blood vessels that act as a filter in the nephron.<\/div><\/div>
<\/a>Glucose degradation products (GDPs)<\/strong>
Products resulting from the degradation (break down) of glucose during heat sterilization of the dialysate, which are believed to be toxic to the peritoneal membrane. Glucose can bind in a non-enzymatic way to amino residues forming a Schiff base and later a reversible Amadori glycosylation product. These products undergo rearrangements over time and form irreversible advanced glycation end products (AGEs), which may play a role in the development of peritoneal fibrosis and microvascular sclerosis, observed in long term PD patients. Formation of GDP can be significantly reduced by the use of multi-chamber bag systems.<\/div><\/div>
<\/a>Gram<\/strong>
The basic unit of weight measure in the metric system. There are approximately thirty grams in one ounce.<\/div><\/div>
<\/a>Gross Domestic Product (GDP)<\/strong>
The total monetary or market value of all the finished goods and services produced within a country within a specific time period.<\/div><\/div>
<\/a>Gross peritoneal surface area<\/strong>
The anatomical surface area of the peritoneal membrane lining the peritoneal cavity.<\/div><\/div>
<\/a>Hand Crank<\/strong>
Relating to the hemodialysis machine: Method used to return blood to the patient during a power failure, also know as Emergency Hand Crank, that utilizes the auxiliary blood pump crank handle inserted into the hand crank spindle on the blood pump and the blood is manually returned to the patient.<\/div><\/div>
<\/a>Hazard ratio (HR)<\/strong>
A measure of the probability of an event in one group compared to that of a control group over a particular time. A hazard ratio greater than 1 indicates an increased risk, while a hazard ratio below 1 indicates a smaller risk.<\/div><\/div>
<\/a>Headache <\/strong>
Pain in the cranial region that may occur as an isolated and benign symptom or as a manifestation of a wide variety of conditions.<\/div><\/div>
<\/a>Health-related quality of life (HRQoL)<\/strong>
An individual\u2019s or group\u2019s perceived physical and mental health over time.<\/div><\/div>
<\/a>Hemastix<\/strong>
Monitoring strip that identifies the presence of blood.<\/div><\/div>
<\/a>Hematocrit<\/strong>
A measurement of red cells in the blood, stated as a percentage of red blood cells per total blood volume.<\/div><\/div>
<\/a>Hematoma<\/strong>
An accumulation of blood that has escaped into the tissues from blood vessels. It is commonly referred to as a bruise and appears \"black and blue\".<\/div><\/div>
<\/a>Hemodialysis<\/strong>
A process of removing chemical substances and water from the blood by passing it through an artificial kidney composed of semi-permeable membranes.<\/div><\/div>
<\/a>Hemoglobin<\/strong>
Protein found in erthrocytes that transports oxygen in the blood.<\/div><\/div>
<\/a>Hemolysis<\/strong>
The destruction of red blood cells resulting in the liberation of haemoglobin, potassium and other cell contents.<\/div><\/div>
<\/a>Hemorrhage<\/strong>
Abnormal bleeding, either internal or external.<\/div><\/div>
<\/a>Heparin<\/strong>
A powerful anticoagulant that blocks\/suppresses clotting of the blood. In peritoneal dialysis heparin can be added to the dialysis solution. Heparin inhibits the formation of fibrin and may prevent subsequent adhesion formation.<\/div><\/div>
<\/a>Heparin Pump<\/strong>
A component of the hemodialysis delivery system that delivers heparin at a prescribed rate.<\/div><\/div>
<\/a>Hepatitis<\/strong>
An inflammation of the liver, can be of viral or toxic origin.<\/div><\/div>
<\/a>Homeostasis<\/strong>
State of equilibrium of the internal environment of the body that is maintained by dynamic processes of feedback and regulation.<\/div><\/div>
<\/a>Hydrostatic Pressure<\/strong>
The pressure exerted by a column of water due to gravity or mechanical pressure.<\/div><\/div>
<\/a>Hyperkalaemia<\/strong>
Unusually high levels of potassium in the blood.<\/div><\/div>
<\/a>Hyperparathroidism<\/strong>
Primary hyperparathyroidism is a disorder of the parathyroid glands, also called parathyroids. \"Primary\" means this disorder originates in the parathyroids: One or more enlarged, overactive parathyroid glands secretes too much parathyroid hormone (PTH). In secondary hyperparathyroidism, a problem such as kidney failure causes the parathyroids to be overactive.<\/div><\/div>
<\/a>Hypertension<\/strong>
Blood pressure greater than normal.<\/div><\/div>
<\/a>Hyperthermia<\/strong>
Abnormally high body temperature.<\/div><\/div>
<\/a>Hypertrophy<\/strong>
An increase in size of an organ or structure that does not involve tumor formation.<\/div><\/div>
<\/a>Hypervolemia<\/strong>
Abnormally increased volume of circulating blood in the body.<\/div><\/div>
<\/a>Hypokalaemia<\/strong>
Not enough potassium in the blood.<\/div><\/div>
<\/a>Hypoperfusion<\/strong>
Decreased blood flow through an organ, as in circulatory shock. If prolonged, it may result in permanent cellular dysfunction and death.<\/div><\/div>
<\/a>Hypotension<\/strong>
Low blood pressure.<\/div><\/div>
<\/a>Hypothermia<\/strong>
Abnormally low body temperature.<\/div><\/div>
<\/a>Hypotonic<\/strong>
A solution with an osmolality or concentration of solutes less than that which it is compared. In dialysis, the fluid of comparison is usually blood.<\/div><\/div>
<\/a>Hypovolemia<\/strong>
Abnormally decreased volume of circulating blood in the body.<\/div><\/div>
<\/a>Hypoxia<\/strong>
Clinical manifestation of respiratory distress consisting of a relatively complete absence of oxygen.<\/div><\/div>
<\/a>Icodextrin<\/strong>
Usually a 20 glucose polymer molecule which is used as an agent inducing ultrafiltration by oncotic pressure. [From the Greek word for twenty: eicosi or ico(si) + dextrin = icodextrin].<\/div><\/div>
<\/a>Infection<\/strong>
Invasion of the body by disease producing organisms and the reaction of the tissues to their presence.<\/div><\/div>
<\/a>Infiltration<\/strong>
In hemodialysis, this is referred to as the dislodgment of the fistula needle from the patient\u2019s access which results in blood being returned to the surrounding tissues.<\/div><\/div>
<\/a>Inflow time<\/strong>
The time needed for the fresh dialysate to enter the peritoneal cavity.<\/div><\/div>
<\/a>Intention-to-treat analysis<\/strong>
An analysis in which all patients who were enrolled and randomly allocated to a specific intervention or medication are included in the results analysis and are analyzed in the groups to which they were randomized.<\/div><\/div>
<\/a>Intermittent peritoneal dialysis (IPD)<\/strong>
Intermittent peritoneal dialysis (IPD) IPD generally consists of frequent, short cycles performed over 8 - 10 hours per session, three times weekly. The peritoneal cavity remains drained between sessions. If IPD is practiced on a nightly basis, it is referred to as nocturnal IPD (NIPD). See home page \u201cperitoneal dialysis-modalities\u201d.<\/div><\/div>
<\/a>International Society for Peritoneal Dialysis (ISPD)<\/strong>
A society aimed at advancing knowledge of peritoneal dialysis and promoting PD through international scientific meetings and scientific publications.<\/div><\/div>
<\/a>Intraperitoneal Volume (Vip)<\/strong>
The volume of fluid inside the peritoneal cavity.<\/div><\/div>
<\/a>Isotonic<\/strong>
A solution with an osmolality or concentration of solutes equal to that which it is compared. In dialysis, the fluid of comparison is usually blood.<\/div><\/div>
<\/a>KDOQI (Kidney Disease Outcomes Quality Initiative)<\/strong>
Guidelines from the National Kidney Foundation aimed at improving the diagnosis and treatment of kidney disease.<\/div><\/div>
<\/a>Kidney Disease: Improving Global Outcomes (KDIGO)<\/strong>
A global nonprofit organization developing and implementing evidence-based clinical practice guidelines in kidney disease.<\/div><\/div>
<\/a>Kidney Failure Treatment Choices model, or ESRD Treatment Choices (EST) Model<\/strong>
A mandatory payment model focused on encouraging greater use of home dialysis and kidney transplants, to reduce Medicare expenditures while preserving or enhancing the quality of care furnished to Medicare beneficiaries.<\/div><\/div>
<\/a>Kilogram<\/strong>
1,000 grams; 2.2 pounds.<\/div><\/div>
<\/a>Kt\/V<\/strong>
The Kt\/V concept was introduced by Gotch and Sargent to quantitate dialysis dose and represents the product of urea clearance (K) and dialysis time (t) divided by the volume of distribution of urea or total body water (V)3. Kt\/V is different in hemodialysis (HD) compared to peritoneal dialysis (PD). In HD, Kt\/V relates to a single dialysis session, whereas in PD Kt\/V relates to an entire week.<\/div><\/div>
<\/a>KUF<\/strong>
In vivo ultrafiltration constant. The fixed amount of fluid a dialyzer will remove from the patient\u2019s blood per hour at a specified pressure. A dialyzer\u2019s KUF is included with its instructions.<\/div><\/div>
<\/a>Lavage<\/strong>
Peritoneal lavage or flush is the \"rapid\" infusion and drainage of peritoneal dialysis solution with the purpose of removing blood, fibrin, debris or spent dialysate from the peritoneal cavity or catheter. The dwell time is minimal or non-existent.<\/div><\/div>
<\/a>Low-Flow Dialysate<\/strong>
Conventional hemodialysis machines generally employ a high dialysis flow rate, with urea clearance increasing as either blood low or dialysate flow rate increases. At high flow rates, clearance rate per unit of dialysate is lower and the dialysate is minimally saturated, resulting in inefficient dialysate use. By contrast, low-volume, high-efficiency platforms, such as the NxStage System One, provide effective dialysis with very low volumes of dialysate by maintaining a very low ratio of dialysate flow rate to blood flow rate (high blood flow rate relative to the dialysate flow rate). When dialysis is used at a lower flow ratio, the dialysis fluid becomes fully saturated with waste products and this saturation minimizes the amount of dialysis fluid that is needed to achieve a desired urea clearance. This allows for the efficient use of dialysate and minimizes the requirement for storage supply space and the use of water.<\/div><\/div>
<\/a>Luer lock<\/strong>
A type of tubing connector with threaded fittings for a secure connection and added leverage for a seal disconnect. The concept for these adapters was developed by Hermann Wulfing Luer, a German medical instrument maker whose name still defines this unique design.<\/div><\/div>
<\/a>Macrophage<\/strong>
A large scavenger cell present in connective tissue and many major organs and tissues including the bone marrow, spleen, lymph nodes, liver and central nervous cells.<\/div><\/div>
<\/a>Magnetic resonance imaging (MRI)<\/strong>
A type of scan that uses strong magnetic fields and radio waves to produce detailed images of the inside of the body.<\/div><\/div>
<\/a>Mass transfer area coefficient (MTAC)<\/strong>
For a given solute, MTAC is equivalent to the diffusive clearance of that solute per time unit in a theorectical situation where dialysate flow in infinitely high, so that the solute gradient is always maximal (MTAC is analogous to K0A of a hemodialysis membrane and is best assessed at the beginning of each exchange when there is maximum difference in the concentration between blood and dialysate).<\/div><\/div>
<\/a>Matched-cohort study<\/strong>
A study in which individuals from the treatment and control groups are paired based on certain baseline characteristics to reduce confounding factors that can affect the results.<\/div><\/div>
<\/a>Medicaid<\/strong>
A U.S. federal-state assistance program that serves low-income people of every age run by state and local governments within federal guidelines. Patients usually pay no part of costs for covered medical expenses.<\/div><\/div>
<\/a>Medicare<\/strong>
A U.S. federal insurance program that serves people over 65 primarily (whatever their income), younger disabled people, and dialysis patients run by the Centers for Medicare & Medicaid Services, an agency of the US federal government. Patients pay part of healthcare costs through deductibles.<\/div><\/div>
<\/a>Membrane<\/strong>
A thin layer of tissue that covers or surrounds a surface or space. In dialysis,it can refer to either the peritoneal membrane or the material out of which the internal fibres of the artificial kidney are composed.<\/div><\/div>
<\/a>Membrane failure<\/strong>
The inability of the peritoneal membrane to maintain adequate ultrafiltration or adequate solute clearance.<\/div><\/div>
<\/a>Metabolism<\/strong>
The sum of all physical and chemical changes that take place within an organism. All energy and material transformations that occur within living cells.<\/div><\/div>
<\/a>Modality<\/strong>
A means or manner in which a procedure is attained.<\/div><\/div>
<\/a>Molecule<\/strong>
Smallest particle of a substance with distinct chemical properties that identify the substance; stable group of atoms.<\/div><\/div>
<\/a>Morbidity<\/strong>
Pertaining to disease or illness.<\/div><\/div>
<\/a>Mortality<\/strong>
Pertaining to death or loss of life.<\/div><\/div>
<\/a>Myalgia<\/strong>
Tenderness or pain in the muscles.<\/div><\/div>
<\/a>National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)<\/strong>
Institute within the U.S. National Institute of Health (NIH), the United State\u2019s medical research agency, which conducts and supports biomedical research.<\/div><\/div>
<\/a>Nausea<\/strong>
An unpleasant sensation in the stomach usually accompanied by the urge to vomit.<\/div><\/div>
<\/a>Nephritis<\/strong>
Inflammation of the kidney. A disease of the kidneys haematuria associated with a nephritic syndrome that includes hematuria as its distinguishing component. Other classic symptoms include hypertension, renal insufficiency, volume overload, oedema, and in some cases, proteinuria.<\/div><\/div>
<\/a>Nephrologist<\/strong>
A physician who specializes in kidney diseases and their treatment.<\/div><\/div>
<\/a>Nephron<\/strong>
The structural and functional unit of the kidney. It consists of a glomerulus enclosed within Bowman's capsule and its attached tubule (consists of proximal convoluted tubule, loop of Henle and distal convoluted tubule). Urine is formed by filtration in the glomerulus, and selective reabsorption and secretion by cells of the renal tubule.<\/div><\/div>
<\/a>Net sieving coefficient<\/strong>
The fraction of extracellular solute volume removed per unit of ultrafiltrate volume.<\/div><\/div>
<\/a>Observational study<\/strong>
A study in which individuals are observed or certain outcomes are measured with no interference or manipulation of the research subjects by the investigator to affect the outcome. For example, a study investigating the effect of a treatment on patients in which the assignment of subjects into a treated or control group is not determined by the researcher.<\/div><\/div>
<\/a>Occlude<\/strong>
To shut or close off.<\/div><\/div>
<\/a>Oedema<\/strong>
Excess fluid in the body tissues; swelling of the body due to excess fluid.<\/div><\/div>
<\/a>Oliguria<\/strong>
Decreased amount of urine formation.<\/div><\/div>
<\/a>Osmolality<\/strong>
The osmotic concentration characteristic of a solution that is determined by the ionic concentration of the dissolved substance per unit of solvent.<\/div><\/div>
<\/a>Osmolarity<\/strong>
The concentration of osmotically active particles in solution.<\/div><\/div>
<\/a>Osmosis<\/strong>
Passage of fluid through a semi-permeable membrane from an area of lesser concentration to an area of greater concentration in order to achieve equilibrium of solute.<\/div><\/div>
<\/a>Osteitis Fibrosa Cystica<\/strong>
Tissue level lesions, fibrosis of the marrow spaces and abundance of osteoclasts. Is characterized by severely increased bone resorption and high levels of parathyroid hormone (PTH).<\/div><\/div>
<\/a>Out-center Hemodialysis (OCHD)<\/strong>
Hemodialysis carried out at self-care HD units, which were developed as an alternative answering the requirements of autonomous patients who do not have the possibility to be treated at home.<\/div><\/div>
<\/a>Outcome<\/strong>
End product or result.<\/div><\/div>
<\/a>Palpable<\/strong>
Perceptible to touch.<\/div><\/div>
<\/a>Palpitation<\/strong>
Irregular beating of the heart<\/div><\/div>
<\/a>Pericardial Effusion<\/strong>
Fluid in the pericardial cavity, between the visceral and parietal pericardium. It may produce symptoms of cardiac tamponade (see above for definition)<\/div><\/div>
<\/a>Pericarditis<\/strong>
Inflammation of the pericardium, or sac surrounding the heart.<\/div><\/div>
<\/a>Peritoneal catheter cuff<\/strong>
A band of fabric (e.g. Dacron) affixed to the intratunnel part of the catheter leading to pericatheter fibrous tissue growth. Usually, peritoneal catheters have two cuffs, one located close to the endoabdominal fascia (deep or epiperitoneal or inner or internal cuff) and the other located close to the skin (outer or subcutaneous or superficial or external cuff).<\/div><\/div>
<\/a>Peritoneal catheter tunnel<\/strong>
The passageway through the abdominal wall within which the peritoneal catheter is contained.<\/div><\/div>
<\/a>Peritoneal dialysis (PD) training<\/strong>
The procedure of preparing an individual with ESRD for the self administration of the PD treatment, including preparation of materials, aseptic technique, prevention of contamination, exit site care, performing exchanges, troubleshooting, record keeping, and ordering supplies. PD training is usually provided by a specially trained nurse.<\/div><\/div>
<\/a>Peritoneal dialysis catheter<\/strong>
See catheter. The intraperitoneal and the extraperitoneal potions differ in various catheters. The most commonly used type of catheter is the Tenckhoff catheter (straight, coiled, or swan-neck design). Modifications of the Tenckhoff catheter are the Missouri swan-neck catheter, the Moncrief-Popovich swan-neck catheter and the Toronto Western Hospital (TWH) or Oreopoulos-Zellerman catheter.<\/div><\/div>
<\/a>Peritoneal dialysis connectology<\/strong>
A conventional term referring to the various systems of transfer sets, connecting devices, containers, adapters, etc., which are used during the process of peritoneal dialysis.<\/div><\/div>
<\/a>Peritoneal dialysis dose<\/strong>
The amount of dialysate used in a specified time. It can be numerically expressed by Kt\/V or creatinine clearance and should be corrected to either the total body water or body surface area.<\/div><\/div>
<\/a>Peritoneal dialysis prescription<\/strong>
The combination of peritoneal dialysis modality, dose and schedule.<\/div><\/div>
<\/a>Peritoneal eosinophilia (Former term: Eosinophilic peritonitis)<\/strong>
Asymptomatic cloudy effluent with more than 15% eosinophils in a differential WBC count. It usually appears in the first few months after starting PD and is usually a benign self-limiting condition. (Peritoneal eosinophilia can also occur later during some fungal infections).<\/div><\/div>
<\/a>Peritoneal equilibration test (PET)<\/strong>
See https:\/\/fmc.mindquestlearning.com\/content\/understanding-testing-methods<\/a><\/div><\/div>
<\/a>Peritoneal sclerosis<\/strong>
The extensive thickening of the peritoneal membrane due to fibrous tissue and new vessel formation, usually as a result of long-term PD, especially when the latter is complicated by severe or recurrent peritonitis.<\/div><\/div>
<\/a>Peritonitis<\/strong>
Peritonitis is an inflammation of the peritoneum. Infectious peritonitis is inflammation of the peritoneum related to microorganisms. Resistant or refractory peritonitis is an episode that does not respond to treatment within 48 hours. Relapsing peritonitis is an episode that initially responds to treatment but then symptoms reappear. Recurrent peritonitis is an episode with symptoms that return within 2 weeks of the completion of therapy for peritonitis and the organism is the same as in the prior episode.<\/div><\/div>
<\/a>pH<\/strong>
The hydrogen ion concentration of a solution. A solution with a pH above 7 is alkaline (base). A solution with a pH below 7 is an acid.<\/div><\/div>
<\/a>Phosphate Binder<\/strong>
Compounds that bind phosphorus in the GI tract, preventing absorption. Bound phosphorus becomes part of the faeces and is eliminated. Classes of binders include aluminum, calcium and magnesium as well as non-absorbable calcium and aluminum-free compounds.<\/div><\/div>
<\/a>Phosphorus<\/strong>
Is a nonmetallic element present in such foods as dairy products, meats, fish, nuts, chocolate and cola. Too much phosphorus in the blood can cause itching, secondary hyperparathroidism and bone disease.<\/div><\/div>
<\/a>Plasma<\/strong>
The straw coloured, non-cellular liquid portion of the blood containing clotting factors. It consists of water, electrolytes, nutrients and proteins.<\/div><\/div>
<\/a>Polyglucose<\/strong>
Mixture of glucose polymers in different chain lengths.<\/div><\/div>
<\/a>Pore<\/strong>
Small opening or hole.<\/div><\/div>
<\/a>Postural Hypotension<\/strong>
The development of hypotension when the posture is changed. This is usually manifested by dizziness on standing.<\/div><\/div>
<\/a>Potassium<\/strong>
A metallic element, and an important electrolyte in the human body, Levels of potassium that are too high or too low can cause illness or death, levels must be kept within very tight limits.<\/div><\/div>
<\/a>Prescription<\/strong>
Directions written for the preparation and administration of a therapy.<\/div><\/div>
<\/a>Prime<\/strong>
Procedure done before hemodialysis to remove air from the extracorporeal circuit by flushing the bloodlines and dialyzer with saline.<\/div><\/div>
<\/a>PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses)<\/strong>
An evidence-based guideline setting up the minimum items for reporting in systematic reviews and meta-analyses.<\/div><\/div>
<\/a>Prospective study<\/strong>
A type of observational study in which participants are identified and enrolled, then followed for a period of time to gather pertinent data and record outcomes.<\/div><\/div>
<\/a>Protein<\/strong>
A group of nitrogen-containing compounds found widely in nature in both plants and animals. They are formed from complex combinations of amino acids. They form structural material of muscles, tissues and organs. They form enzymes and hormones.<\/div><\/div>
<\/a>Proximal<\/strong>
Nearest the point of attachment, centre of the body or point of reference. Opposite of distal.<\/div><\/div>
<\/a>Pruritis<\/strong>
Intense itching.<\/div><\/div>
<\/a>Pulmonary Oedema<\/strong>
An accumulation of fluid in the lungs caused by fluid overload.<\/div><\/div>
<\/a>Pulse<\/strong>
Rhythmical throbbing caused by the regular expansion and contraction of an artery.<\/div><\/div>
<\/a>PVC<\/strong>
PVC Abbreviation for polyvinyl chloride<\/div><\/div>
<\/a>Pyrogen<\/strong>
A substance that causes fever.<\/div><\/div>
<\/a>RAND 36-Item Health Survey (RAND-36, or RAND)<\/strong>
Health-related quality of life survey instrument, which is comprised of 36 items assessing eight health concepts: physical functioning, role limitations caused by physical health problems, role limitations caused by emotional problems, social functioning, emotional well-being, energy\/fatigue, pain, and general health perceptions. Physical and mental health summary scores are also derived from the eight RAND-36 scales.<\/div><\/div>
<\/a>Randomized study<\/strong>
A study in which individuals are randomly allocated into separate groups (treatment versus control) to compare different comparison groups and avoid bias.<\/div><\/div>
<\/a>Recurrent peritonitis<\/strong>
A peritonitis episode that occurs within 4 weeks of completion of therapy of a prior episode but with a different organism.<\/div><\/div>
<\/a>Red Blood Cell (RBC)<\/strong>
Cells in the blood stream that carry oxygen in a complete molecule called haemoglobin.<\/div><\/div>
<\/a>Refractory peritonitis<\/strong>
Failure of the effluent to clear after 5 days of appropriate antibiotic therapy<\/div><\/div>
<\/a>Regimen<\/strong>
A regimen is a systematic plan of therapy that is generally characterized as intermittent or continuous when referring to the duration of dialysis, and supine or ambulatory when referring to the position of the patient (for PD).<\/div><\/div>
<\/a>Relapsing peritonitis<\/strong>
A peritonitis episode that occurs within 4 weeks of completion of therapy of a prior episode of peritonitis with the same organism or a prior sterile episode.<\/div><\/div>
<\/a>Renal<\/strong>
Pertaining to the kidneys.<\/div><\/div>
<\/a>Renal Osteodystrophy<\/strong>
Generalized bone disease resulting from metabolic disorder caused by renal failure.<\/div><\/div>
<\/a>Repeat peritonitis<\/strong>
A peritonitis episode that occurs more than 4 weeks after completion of therapy of a prior episode with the same or different organism.<\/div><\/div>
<\/a>Respite Care<\/strong>
Temporary or part-time care provided by a healthcare professional in a healthcare facility to provide short-term relief for the primary caregiver of a person with chronic kidney disease on dialysis. This option allows home hemodialysis patients to continue their prescribed treatments in-center for a short period of time, giving care providers the freedom to take time off. Reasons for respite care in this study included access dysfunction, puncture difficulties, AVF infection or other infection, retraining, complementary work-up, training for vacation using NxStage for patients that had been using a conventional device, or technical problems at home with the dialysis machine or the water treatment system.<\/div><\/div>
<\/a>Restless Leg Syndrome<\/strong>
Is a condition that is characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations. It most commonly affects the legs, but can also affect the arms or torso.<\/div><\/div>
<\/a>Reverse Osmosis (RO)<\/strong>
A method for purifying water by forcing it through a semi-permeable membrane that prevents the passage of ions.<\/div><\/div>
<\/a>Rinse Back Volume<\/strong>
Amount of saline required to rinse the patient\u2019s blood back following completion of the hemodialysis treatment.<\/div><\/div>
<\/a>Rotor<\/strong>
The rotating part of an electronic or mechanical device.<\/div><\/div>
<\/a>Rx<\/strong>
Abbreviation for \"Prescription\".<\/div><\/div>
<\/a>Semi-permeable Membrane<\/strong>
A membrane with pores that are permeable to some (smaller molecules) but not to larger molecules.<\/div><\/div>
<\/a>Sequential Dialysis<\/strong>
Two-stage form of hemodialysis treatment in which the first stage consists only of ultrafiltration. In the first stage, there is no dialysate flow while the ultrafiltration pump draws excess fluid from the patient. After the calculated amount of fluid has been drawn, usually a standard dialysis treatment, begins.<\/div><\/div>
<\/a>Shock<\/strong>
Extreme hypotension.<\/div><\/div>
<\/a>Short Form 36 Health Survey (SF-36)<\/strong>

A generic 36-item self-report measure of health-related quality of life. It yields an 8-scale profile that is integrated into two summary measures:\r\n
\r\n\u2022 Physical Component Score (PCS): includes dimensions of the physical functioning, role-physical, bodily pain, and general health scales, as well as elements of the vitality and social functioning scales.\r\n
\r\n\u2022 Mental Component Score (MCS): comprised of the role-emotional, and mental health scales, and it also includes elements of the general health, vitality, and social functioning scales.\r\n\r\n<\/pr><\/div><\/div>

<\/a>Sodium<\/strong>
Chief cation of the extracellular body fluids. Its salts are the most widely used in medicine. Physiologically the sodium ion plays a major role in blood pressure regulation, maintenance of fluid volume, and electrolyte balance.<\/div><\/div>
<\/a>Solute<\/strong>
The substance that is dissolved in a liquid (solvent) to form a solution.<\/div><\/div>
<\/a>Sphygmomanometer<\/strong>
An instrument used to measure blood pressure.<\/div><\/div>
<\/a>Standard Kt\/V<\/strong>
The stdKt\/V is a formula to measure the relative efficiency of the whole spectrum of dialytic therapies whether intermittent, continuous or mixed. This method allows the measurement of clearance efficiency of HD of variable frequency, continuous PD, intermittent PD, slow continuous renal replacement therapies (CRRT), residual renal function (RRF) and all situations involving the use of clearance from various methods.<\/div><\/div>
<\/a>Steal Syndrome<\/strong>
Pain or weak pulse in affected limb caused by shunting of normal arterial blood supply through the access thus depriving distal extremity of needed oxygenation.<\/div><\/div>
<\/a>Sterile<\/strong>
Completely free from living microorganisms.<\/div><\/div>
<\/a>Sterile peritonitis<\/strong>
Synonym to culture-negative peritonitis<\/div><\/div>
<\/a>Stethoscope<\/strong>
A device used to auscultate (listen to) sounds produced by the body. It consists of rubber tubing connecting two ear pieces to a diaphragm and\/or bell.<\/div><\/div>
<\/a>Supine position<\/strong>
Lying with the face upward, or on the dorsal surface.<\/div><\/div>
<\/a>Syringe<\/strong>
Instrument used for injecting or withdrawing fluids.<\/div><\/div>
<\/a>Systolic Blood Pressure<\/strong>
This is the pressure inside arteries during a heartbeat. This is the top half of the blood pressure reading.<\/div><\/div>
<\/a>T-set<\/strong>
A variant of the double-bag system, which consists of a catheter extension equipped with a very short lateral limb, through which, at the end of the exchange, before the disconnection of the bag, a disinfectant is injected filling the catheter extension.<\/div><\/div>
<\/a>Tachycardia<\/strong>
An abnormally fast heart rate. If 70 to 90 beats per minute is considered normal, then 100 beats per minute would indicate tachycardia.<\/div><\/div>
<\/a>Technique<\/strong>
A technique is the procedure by which a regimen is accomplished. These definitions can be confusing since similar terms are applied to the regimen and the technique.<\/div><\/div>
<\/a>Technique failure rate<\/strong>
The proportion of peritoneal dialysis patients switching to hemodialysis<\/div><\/div>
<\/a>Tetany<\/strong>
A set of symptoms which include intermittent tonic spasms, nervousness and muscular irritability induced by changes in calcium or pH.<\/div><\/div>
<\/a>Three-pore model<\/strong>
A theoretical model describing solute and water transport across the peritoneal membrane Proposing the presence of three different sizes of pores. The smallest are considered to be the aquaporins.<\/div><\/div>
<\/a>Thrombus<\/strong>
Clot formed in a blood vessel or blood passage.<\/div><\/div>
<\/a>Tidal peritoneal dialysis<\/strong>
See https:\/\/fmc.mindquestlearning.com\/content\/pd-modalities<\/a><\/div><\/div>
<\/a>Titanium (or plastic) adaptor<\/strong>
The Luer lock adaptor made of titanium (or plastic), connecting the catheter to its extension or to the administration set of a double-bag system.<\/div><\/div>
<\/a>TMP (Transmembrane Pressure)<\/strong>
The difference in pressure between the filtrate and permeate sides of the dialyzer membrane. TMP = Venous Pressure \u2013 Dialysate Pressure.<\/div><\/div>
<\/a>Transducer<\/strong>
An electronic sensor in the hemodialysis machine that reads the pressure inside the arterial and venous drip chambers. Transducers are connected to the drip chambers through pressure monitor lines.<\/div><\/div>
<\/a>Transfer set<\/strong>
The tubing connecting the catheter to the dialysate bag in the non-disconnecting system<\/div><\/div>
<\/a>Tunnel infection<\/strong>
Erythema, edema or tenderness or any combination of these over the subcutaneous portion of the catheter<\/div><\/div>
<\/a>Ultrafiltrate<\/strong>
In peritoneal dialysis, the net amount of fluid resulting when the original volume of the dialysate used for a certain dwell is subtracted from the volume of the drained dialysate(effluent-infused dialysate = ultrafiltrate).<\/div><\/div>
<\/a>Ultrafiltration<\/strong>
The process by which plasma water is removed from the blood related to an osmotic pressure gradient. The rate of ultrafiltration is highest in the beginning of an exchange when the osmotic gradient is highest.<\/div><\/div>
<\/a>Ultrafiltration failure<\/strong>
The inability of the peritoneal membrane to provide adequate ultrafiltration.<\/div><\/div>
<\/a>United States Renal Data System (USRDS)<\/strong>
A national data registry that collects information about chronic kidney disease (CKD) and end-stage kidney disease (ESKD) in the United States. It is funded directly by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and collaborates with the Center for Medicare & Medicaid Services (CMS), the United Network for Organ Sharing (UNOS), and the ESKD networks, sharing datasets and working to improve the accuracy of ESKD patient information.<\/div><\/div>
<\/a>Universal Precautions<\/strong>
Those necessary safeguards based upon the assumption that all human blood and certain human body fluids are treated as if they are known to be infectious for any blood borne pathogens.<\/div><\/div>
<\/a>Urea<\/strong>
Waste products formed by the breakdown of protein in the body.<\/div><\/div>
<\/a>Uremia<\/strong>
Toxic condition that develops in kidney failure due to the accumulation of waste products in the blood that are normally excreted in the urine.<\/div><\/div>
<\/a>Uremic Frost<\/strong>
A white, powder-like substance that results from the precipitation of urea crystals secreted in the sweat. It may be seen on the face and trunk. Unusual to see today as dialysis usually begins before this develops.<\/div><\/div>
<\/a>Vein<\/strong>
Blood vessel that carries deoxygenated blood toward the heart from other parts of the body.<\/div><\/div>
<\/a>Venous Drip Chamber<\/strong>
Chamber within the hemodialysis extracorporeal circuit where venous pressure is monitored. A bubble trap inside the drip chamber collects any air that enters the blood tubing.<\/div><\/div>
<\/a>Venous Pressure<\/strong>
The pressure within the venous drip chamber of the hemodialysis extracorporeal circuit.<\/div><\/div>
<\/a>Vital Signs<\/strong>
Blood pressure, temperature, pulse and respiration.<\/div><\/div>
<\/a>Vomiting<\/strong>
The forcible expulsion of the contents of the stomach through the mouth.<\/div><\/div><\/div><\/div>