

{"id":1346,"date":"2020-03-28T02:24:44","date_gmt":"2020-03-28T07:24:44","guid":{"rendered":"https:\/\/ami.advancedrenaleducation.com\/wparep\/?post_type=article&#038;p=1346"},"modified":"2025-05-09T16:55:04","modified_gmt":"2025-05-09T21:55:04","slug":"how-to-achieve-adequate-pd-uf","status":"publish","type":"article","link":"https:\/\/ami.advancedrenaleducation.com\/wparep\/article\/how-to-achieve-adequate-pd-uf\/","title":{"rendered":"How to Achieve Adequate PD UF"},"content":{"rendered":"<p>The most effective ways of increasing ultrafiltration (UF) are increasing the concentration of glucose in the dialysis solution and providing shorter and more frequent exchanges. The latter is most effective among patients with high peritoneal transport since a short exchange can occur while the osmotic gradient is still considerably high<\/p>\n<p align=\"center\"><span style=\"color: #000000;\"><strong><a href=\"https:\/\/ami.advancedrenaleducation.com\/wparep\/wp-content\/uploads\/2020\/03\/UF-rate-vs-time-for-various_0.gif\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-1348\" src=\"https:\/\/ami.advancedrenaleducation.com\/wparep\/wp-content\/uploads\/2020\/03\/UF-rate-vs-time-for-various_0.gif\" alt=\"\" width=\"450\" height=\"375\" \/><\/a><\/strong><\/span><\/p>\n<h6 align=\"center\"><span style=\"color: #000000;\">UF rate vs time for various dextrose concentrations<\/span><\/h6>\n<p align=\"justify\">With automated peritoneal dialysis (APD) it is relatively easy to increase ultrafiltration by simply prescribing shorter and more exchanges during the night without taxing patient\u2019s time.\u00a0 However, high transporters do not experience enough UF during the long diurnal exchanges of CCPD.\u00a0 This creates a problem since we should avoid the excessive use of highly hypertonic solutions (4.25% dextrose) due to the increased caloric load and potentially deleterious effects on the peritoneal membrane.\u00a0 The ways of maintaining UF during the diurnal phase of APD are by either shortening the dwell time by adding an additional diurnal exchange (see <em>Peritoneal Dialysis (PD) Modalities<\/em> section of the Peritoneal Dialysis article for more) or with the use of polyglucose-containing solutions.\u00a0 The application of two shorter exchanges using glucose can provide the same or higher ultrafiltration as polyglucose, makes it possible to avoid 4.25% dextrose concentrations in most cases and avoids the adverse effects associated with polyglucose.<\/p>\n<p align=\"justify\"><a href=\"https:\/\/ami.advancedrenaleducation.com\/wparep\/wp-content\/uploads\/2020\/03\/UF-with-glucose-and-polyglucose-lg.gif\" target=\"_blank\" rel=\"noopener noreferrer\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-1347\" src=\"https:\/\/ami.advancedrenaleducation.com\/wparep\/wp-content\/uploads\/2020\/03\/UF-with-glucose-and-polyglucose-lg.gif\" alt=\"\" width=\"700\" height=\"346\" \/><\/a><\/p>\n<div class=\"vcex-spacing\" style=\"height:30px\"><\/div>\n","protected":false},"featured_media":0,"template":"","format":"standard","meta":{"_acf_changed":false},"categories":[5],"tags":[75],"language":[41],"articles":[266],"class_list":["post-1346","article","type-article","status-publish","format-standard","hentry","category-articles","tag-ultrafiltrationpd","language-english","articles-peritoneal-dialysis","entry","no-media"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>How to Achieve Adequate PD UF - Advanced Renal Education Program<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ami.advancedrenaleducation.com\/wparep\/article\/how-to-achieve-adequate-pd-uf\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How to Achieve Adequate PD UF - Advanced Renal Education Program\" \/>\n<meta property=\"og:description\" content=\"The most effective ways of increasing ultrafiltration (UF) are increasing the concentration of glucose in the dialysis solution and providing shorter and more frequent exchanges. 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